CRISPRing or RISKing? Dangers Arising from Gene Editing with CRISPR-Cas9

Authors: Antonis Giakountis*

DOI: 10.23880/macij-16000114

Volume 2, Issue 2

Abstract

Since its first experimental demonstration in 2007 [1], CRISPR-Cas9 (short for Clustered Regularly Interspaced Short Palindromic Repeats – CRISPR-Associated protein 9) brought a revolution in biology, especially in the fields of gene editing [2] and precision medicine [3]. CRISPR offers several advantages, namely accuracy [4], flexibility [5], versatility [6] and cost reduction [7] that collectively designate it as the most popular approach for gene editing [8], supplanting in parallel other technologies such as TALENs [9] and ZFNs [10].

Keywords: Experimental Demonstration; CRISPR; Medicine

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