ISSN: 2639-2178
Study of Genetic Mutation CSF1R and EPM2A Genes in Patients with Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Syndrome, Iran
In this study we have analyzed 100 people. 40 patients and 60 control group had Adult-onset Leukoencephalopathy with
Axonal Spheroids and Pigmented Glia Syndrome. The gene CSF1R (colony-stimulating factor 1 receptor) analyzed in
terms of genetic mutations made. In this study, people who have genetic mutations were targeted, with nervous
disorders, Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Syndrome. In fact, of all people
with Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Syndrome, 40 people had a genetic
mutation in the genes EPM2A and CSF1R. Any genetic mutations in the target genes control group did not show.
Keywords:
Genetic study; Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Syndrome;
Mutation CSF1R and EPM2A genes; Real Time PCR