Comparison between the Effect of Clindamycin after OpenReduction Internal Fixation in Jaws and in Limbs

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DOI: 10.23880/jobd-16000159

Volume 2, Issue 2

Abstract

Clindamycin is one of the most important antibiotics used against bone infections, in this study we tried to reveal if there is difference between clindamycin effect after open reduction internal fixation (ORIF) in upper and lower jaw operations and the clindamycin effect in open reduction internal fixation (ORIF) of the upper and lower limb bones operations, and to know if the presence of anaerobic bacteria in the oral cavity make any difference of this drug effect comparing with elsewhere bones. We prepared retrospective study about 260 in-patients during the last 10 years, 130 of them after open reduction internal fixation in limb bones and 130 patients after open reduction and internal fixation ORIF in maxillofacial region, given I.V. Clindamycin. There is no significant difference in the effectiveness of clindamycin in the presence of anaerobic bacteria or not, and clindamycin is the drug of choice in prevention against bone infections after open reduction surgery in the orthopedic and maxillofacial purposes which is agreeing with other studies.

Keywords: Bone Infections; Clindamycin; Dental Infections; Prophylaxis Antibiotics

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