Betaine Potentials to Prevent Diabetes and Diabetic Complications: What Hindered the Favorable Clinical Trial Outcomes and What to do?

Authors: Mina T Kelleni

DOI: 10.23880/doij-16000185

Volume 3, Issue 3

Abstract

Betaine, also known as trimethylglycine, is a major water-soluble component of Lyciumchinense and widely distributed in animals, plants, and microorganisms. It acts mainly as an important osmoprotectant as well as oxidative metabolite of choline by suppressing superoxide-induced free radicals through donation of methyl groups and was suggested to have beneficial actions in several human diseases, such as obesity, diabetes, cancer, and Alzheimer's disease [1,2].

Keywords: Diabetes; Diabetic Complications; Clinical Trial

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