ISSN: 2474-9214
Authors: Bhat KA, Bhat JA*, Ara R and Sidiq S
Background: To investigate the effect of injection speed of Propofol for induction of anesthesia primarily on blood pressure and secondarily, on time taken for induction of anesthesia and dose of propofol required. Methods: The prospective & interventional, randomized single blind comparative study conducted on 90 patients of both sexes aged 25-55 years of ASA grade I/II admitted to Paras Hospital Gurugram India, a tertiary care Centre, for elective surgeries under general anesthesia. Results: Mean age, sex, weight, height and distribution of patients as per ASA status was comparable among all the three groups as statistically P values were not significant (all P Value = >0.05). The differences of mean dose of Propofol used in mg and mg/kg for induction, mean induction time (seconds), pre and post induction mean systolic blood pressure (mmHg), mean diastolic blood pressure (mmHg) and mean arterial pressure (mmHg) among the studied groups (P50, P100, and inP200) were statistically significant with a p value of <0.05. There was no statistically significant difference between pre and post induction mean heart rate and oxygen saturation. Conclusion: At faster speeds of injection of Propofol, larger doses are required for induction of anesthesia and significant drop in systolic, diastolic and mean arterial pressures while as the time taken for induction of anesthesia was shorter when compared to the injection at slower speeds.
Keywords: Propofol Injection Speed; Intravenous Anesthesia; Hypotension; Mean Arterial Pressure
