Co-Circulation of All Dengue Serotypes among Patients Attending a Tertiary Care Hospital in Kolkata

Authors: Dey M, Sengupta M, Chatterjee RP, Sarkar S, Chatterjee S and Barik G*

Volume 2, Issue 9

Abstract

The Dengue virus (DENV), a mosquito-borne member of the family Flaviviridae, has four distinct serological types DENV 1, DENV 2, DENV 3, and DENV 4. Between August and December 2016, a total of 2938 samples were tested. 658(22.4%) were IgM-positive out of 1654 samples while 298(10.1%) were NS1-positive out of 1284 samples tested. The age group most susceptible to dengue infection was 21-30 years. During monsoon and post monsoon seasons, the number of IgM and NS1 positive cases increased. The outbreak was more prevalent in urban (83.9%) than rural (16.1%) areas. RT-PCR was done for 131 random NS1 positive samples, of which 37(28.2%) were found positive. Circulating serotype was predominantly DEN2 (14), followed by DEN1 (10), DEN3 (8) and DEN4 (4), and one case of co-infection with both DEN1 and DEN4.

Keywords: Dengue; Serotypes; Prevalence; PCR; Kolkata; IgM; NS1

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