ISSN: 2578-4838
Authors: Hanaa MAA*
Diabetes mellitus (DM) defined as a metabolic disorder of multiple etiology, characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. WHO estimated that the number of people with DM worldwide in year 2000 was 177 million, this will increase to at least 336 million by the year 2030, this increase will be in the developing countries (approximately 75% of all persons). In this study we attempt to investigate the effect of DM on serum lipid profile among Saudis subjects with type 2 DM in Aldwadmi Province. Forty five Saudis diabetic patients were randomly selected from two hospitals (ALbejadia Hoapital, ALgimsh hospital) they were coming from different parts of Western of Alrhid. Their ages were between 18- 60 years, with a mean weight of (70.20  11.203)Kg. Thirty apparently healthy non diabetic people were chosen to serve as controls. Their ages were between (20-60) years and with a mean weight of (71.02  13.429) Kg. All patients underwent a clinical and laboratory evaluation and answered standardized questionnaire. Glucose level, total cholesterol, TC, triglyceride, TG, low-density lipoprotein, LDL, and the high–density lipoprotein cholesterol, HDL were measured for all subjects. The mean of fasting blood glucose (FBG) level of diabetic patients was significantly (p=0.001) higher than that of the non diabetic subjects and the same result was shown with random blood glucose (RBG). Significant difference was observed in lipid profile (TC (p = 0.03), TG (p=0.001) of patients compared to control subjects but the difference for HDL is not significant (p= 0.74). The blood lipid concentrations and the blood glucose level are significantly higher among patients compared to the control subjects.
Keywords: Blood Lipid Concentrations; Diabetes Mellitus; Cardiovascular Disease; Lipid Metabolism; Chronic Hyperglycemia
