Neurogenic Stress Effects on the Immune System Functional State

Authors: Fishman B*, Tapbergenov T, Azovceva O, Kulikov V, Khaybullin T, Tkachenko T, Yukhno M, Lole O, Shevnina E, Kazakova O, Nikolaeva K and Amirbekov A

Volume 2, Issue 10

Abstract

According to most researchers, stress is one of the main causes of the ever increasing number of cardiovascular, gastrointestinal, neurologic and other diseases. In addition to acute damage to organs and systems, stress causes exacerbation of chronic diseases, and also suppresses the immune system. Controlled and uncontrolled stress causes reversible and irreversible changes in the body. If reversible changes in controlled stress lead to the development of adaptation to external influences, irreversible changes can lead to the death of the organism. Given the close attention of researchers to stress, research on the mechanisms for developing the body's adaptation to stressful influences is a major problem in modern biology and medicine. At the same time, the stress response is a necessary link in the adaptation of the organism. However, with an overly intense and prolonged exposure to stress factors, the response significantly reduces the overall resistance of the organism, turning stress reaction from an adaptation link to a pathogenesis link of various diseases. Adaptation of the human and animal organism to constantly changing environmental conditions is one of the main problems of medical and biological science.

Keywords: Neurogenic Stress; Immune Response; Adaptation; Disadaptation

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