ISSN: 2577-4360
Authors: D’Angelo G* and Parashuraman S
Unlike nucleic acids and peptides, glycans are template-free biopolymers. Their sequences are not genetically determined, but rather they emerge from the configuration of dedicated cellular synthetic machineries. Glycan assembly on proteins and lipids is accomplished along the biosynthetic pathway with the Golgi complex hosting about 200 different enzymes and additional accessory factors required for glycosylation.
Keywords: Glycosylation; Peptides; Glycans