ISSN: 2640-2653
Authors: Shaheen MNF
Rotavirus group A (RVA) infection is the most important pathogen of acute diarrheal illness in children and the distribution of this virus in the environment represents threats to Public Health. The aim of the current study was to assess the presence, genotyping, and seasonality of rotavirus in the Egyptian environment and diarrheal specimens of Egyptian children (Ë‚ five years of age) with acute gastroenteritis to understand the current status of RVA vaccines and future considerations. In the current study, articles contained data on the presence of RVA in clinical and environmental samples published between 2010-2015 were collected. In total, detection of RVA in diarrheal specimens was ranged from 28.3% to 76.9% with a median of 37.8% of analyzed samples. Detection rate of RVA in raw sewage was ranged from 14% to 68.4% with a median of 27.8% while in treated effluent it was ranged from 2.7% to 21% with a median of 11.4%. On the other hand, detection rate of rotavirus in raw Nile water samples was ranged from 13.9% to 52.9% with a median of 31.2% whereas in drinking water it was detected in 23.3%, with prevalence rates ranged from 9.7% and 20.8% of analyzed samples. Furthermore, RVA G1 and P[4] were the most prevalent genotypes in clinical samples. Also, RVA G1was the most common genotype detected in environmental samples. G3P[8] and G1P[4] were the most common genotypes in clinical samples and environmental samples, respectively, whereas G1P[8] was the second most common genotype in both clinical and environmental samples. Moreover, the highest detection rates of RVA in both clinical and environmental samples were found in cooler months (autumn and winter). The current study provides useful data to policy makers to develop potential strategies to enhance vaccine uptake and overall impact.
Keywords: Gastroenteritis; Environment; Rotavirus; Sewage; Vaccine; Water
