ISSN: 2578-501X
Authors: Katty AR* and Angelica AR
T-cell lymphomas are a heterogeneous group of lymphoid neoplasms, with a broad classification; in which the peripheral T-cell lymphoma not otherwise specified, is the most frequently diagnosed subtype, demonstrating the complexity of this hematopoietic neoplasms, the lack of studies and knowledge, which difficult us to understand the behavior of this great spectrum of malignancies. We present the clinical case of a patient with late diagnosis and systemic involvement, with initial diagnosis of psoriasis and progressive evolution of the lesions to tumoral and exophytic nodular lesions predominantly in axillae and groin, associated with cytopenia and hepatic involvement, peripheral T-cell lymphoma with T follicular helper cell phenotype was confirmed by biopsy and immunophenotypic studies. This entity was recently described and included in the World Health Organization classification of neoplasms of the hematopoietic and lymphoid tissue updated in 2008. It is a rare entity difficult to diagnose, since it shares clinical and histological characteristics with the great variety of peripheral T-cell lymphoma not otherwise specified, mainly with angioinmunoblastic T-cell lymphoma, whose histological findings, cell markers and immunohistochemistry, have allowed to characterize it as an independent variant.
Keywords: T-cell Lymphoma; Peripheral T-cell Lymphoma; Lymphoma; Non-Hodgkin; Follicular T Cell Lymphoma; Follicular Helper T-cell
