Hopes for Curing Cystic Fibrosis Lung Disease by Non-Viral Gene Therapy

Authors: Di Gioia S and Conese M

DOI: 10.23880/oajprs-16000102

Volume 1, Issue 1

Abstract

In 2015, interesting results have been published in a Phase IIb clinical trial for the treatment of cystic fibrosis (CF), and in particular for the lung disease occurring in this genetic syndrome. CF patients were treated with the complementary DNA (cDNA) for CF Transmembrane Conductance Regulator (CFTR) gene complexes with a liposomal formulation and delivered to the upper airways by aeroionisation.

Keywords: Cystic Fibrosis; Lung; Lung Disease; Gene Therapy

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