A Focus on an Atypical Acute Disseminated Encephalomyelitis

Authors: Diatewa JE*, Mpandzou GA, Boubayi Motoula-Latou DA, Sounga-Bandzouzi EP, Obonzo Aloba K and Ossou-Nguiet PM

DOI: 10.23880/nnoaj-16000132

Volume 4, Issue 1

Abstract

Acute Disseminated Encephalomyelitis (ADEM) is a multifocal demyelinating inflammatory disease. It mainly affects the white matter of the central nervous system. It occurs after an infection or vaccination. In sub-Saharan Africa, its data among adults are almost non-existent in literature. We report the first case of atypical post-infectious ADEM, followed-up from December 2017 to December 2018 at neurology unit of medicine department of Makélékélé hospital in Brazzaville (Congo). ADEM is atypical because of the following peculiarities: diagnostic (medullary lesion which is exclusively cervical and associated with Guillain-Barré syndrome), therapeutic (therapy associating cyclophosphamide with corticoids) and outcome (monophasic outcome influenced by a concomitant lesion of the peripheral nervous system; outcome favourable over 10 months).

Keywords: Acute Disseminated Encephalomyelitis; Guillain-Barré Syndrome; Multiple Sclerosis; Brazzaville

View PDF