Synthesis of Benzo [f] Quinoline and its Derivatives: Mini Review

Authors: Dorina Amariucai-Mantu, Mangalagiu II and Antoci V*

DOI: 10.23880/macij-16000133

Volume 3, Issue 1

Abstract

This study exhibit a short review looking the synthesis of benzo[f]quinoline and its derivatives, over the years. The described syntheses highlighted in this manuscript consist in the first Skraup synthesis presented in the literature by Clem and Hamilton, continuing with the photochemical cyclohydrogenation, provided by Loader and Timmons and with a Doebner-Von Miller reaction, reported by Ramann and Cowen.

Keywords: Benzo[f]quinoline derivatives; Skraup reaction; Photochemical cyclohydrogenation; Heterocycloaddition

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