Clinical Dermatology Open Access Journal (CDOAJ)
ISSN: 2574-7800
Research Article
Studies of the Risk Factors for HIV Transmission from Mothers
Who are Seropositive under B+ Option to Children in the MotherTo-Child Transmission Prevention Sites of the City of Bangui
Authors:
Gabouga FL
,
Kobangué L
,
Diemer SH
,
Guerendo P
,
DibertKamba GD
,
Sépou A
and
Grésenguet G
DOI:
10.23880/cdoaj-16000177
Abstract
Introduction: According to the 2016 program data, in pregnant women, the prevalence of HIV infection in Central African Republic was 3.8% with a mother-to-child transmission rate of 6.2%. A program to prevent the transmission of HIV from mother to child has been set up throughout the country. Despite these interventions, the number of infected infants continues to increase. It is in this context that we have proposed to study the rate prevalence of transmission of HIV from mother-to-child under the B + option and to identify the main risk factors associated with it.
Material and methods: This was a cross-sectional study, from 1st January to 31st December 2017 in five mother-to-child transmission prevention sites(MCTPS) in the city of Bangui. The study population consisted of all infants born to HIVpositive mothers followed under the B + option, and to whom the polymerase chain reaction (PCR) screening test was conducted between the 6th Life Week and 18 months.
Results: 293 infants were identified. Antiretroviral therapy was instituted in 95.6% of mothers and antiretroviral prophylaxis was 97.6% in infants. The rate of mother-to-child transmission of HIV was 4.1%. The main risk factors were the absence of antiretroviral therapy, the screening of mothers after childbirth, and maternal pathologies during pregnancy.
Conclusion: The rate of mother-to-child transmission is still high requiring the intensification of preventive measures.
Keywords: HIV-positive mothers; Prevention HIV Option B+; Bangui
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