ISSN: 2642-116X
Authors: Anubha Bajaj*
An exceptional, benign cutaneous adnexal tumour, Syringocystadenoma papilliferum is contemplated to arise from apocrine glands, apo-eccrine glands and infrequently from eccrine glands. Syringocystadenoma papilliferum concurs with conditions such as nevus sebaceous, verrucae, basal cell carcinoma, verrucous carcinoma, condylomata acuminata, apocrine nevi, eccrine or apocrine neoplasm such as tubular apocrine adenoma, apocrine hidrocystoma or papillary apocrine adenoma, trichoadenoma, apocrine cystadenoma, clear cell syringoma, metaplastic adenocarcinoma and ductal carcinoma. Syringocystadenoma papilliferum delineates sebaceous induction also cogitated in dermatofibroma and melanocytic nevi. Exophytic, papillary arrangement with stratified squamous epithelium is cogitated along with ducts lined by bi-layered epithelium. Immune reactivity to carcino-embryonic antigen (CEA), epithelial membrane antigen (EMA), variably gross cystic disease fluid protein -15(GCDFP 15), cytokeratins CK7 and CK19 is delineated. On dermoscopy, an exophytic papillary pattern of growth, centric depression, superficial erosions, crusts or ulcerated lesion and polymorphic blood vessels are demonstrated. Syringocystadenocarcinoma papilliferum and syringocystadenocarcinoma papilliferum in situ are distinct malignant analogues.
Keywords: Verrucous; Condylomata Acuminate; Eccrine; Dermatofibroma; Hamartoma; Pleuri-Potent Cells
