Adverse Effects of Cadmium on the Biochemical and Histopathological Profiles of Chicken Liver

Authors: Milad A and Zahra A

DOI: 10.23880/ijbp-16000158

Volume 4, Issue 3

Abstract

Background: Cadmium is one of the heavy metals which have toxic effects on the various organs and systems of the body. Estimates demonstrate the increased prevalence of cadmium, particularly in industrial regions. In this study, we examined its harmful effects on the liver of chicken.
Forty chickens
Method: Forty chickens were purchased and were randomly divided into four groups. After collecting liver samples, the microscopic slides were prepared in laboratory. Also, the activities of catalase (CAT), superoxide dismutase (SOD) and the levels of malondialdehyde (MDA) were measured.
Results: The normal structure of liver was observed at control group, but hemorrhage and irregularity in the shape and distribution of hepatocytes in treatment groups were observed. The activities of CAT and SOD decreased significantly at treatment groups compared to the control group. Also, the level of MDA increased significantly at treatment groups compared to the control group.

Keywords: Cadmium; Chicken; Liver; Oil Red; Catalase; Superoxide Dismutase; Lipid Peroxidation

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