Applications and Implications of Viral and Non Viral Vectors in Gene Therapy

Authors: Veerareddy PR*

DOI: 10.23880/oajpr-16000176

Volume 3, Issue 2

Abstract

Gene therapy is a new technique which uses genes to treat or prevent diseases. Viruses normally possess strong promoters, which can create high level gene expression in the infected host cells. Gene Therapy is recognized by the mammalian viruses that are offered as potential tool for gene delivery by either as a biological device or as a vehicle to treat the genetic diseases [1]. Gene therapy involves with Adenovirus, Herpes Simplex Virus, Vaccinia Virus vectors and is utilized in the clinical studies. These vectors are generally nonintegrating and not associated with a known risk of genotoxicity. Adenoviruses are with a double-stranded genome to encode genes with both the sense and antisense orientations

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