Experimental Animal Models of Fibrosis: Relevance and Considerations for Translational Health Research

Authors: Bindu S*

DOI: 10.23880/izab-16000150

Volume 2, Issue 3

Abstract

Tissue fibrosis is a set of progressive debilitating diseases which although initiate as a normal wound healing response to an injury, end up with hyperactivated immunological state leading to overwhelming deposition of extra cellular matrix (ECM) components by activated fibroblasts. About 45% deaths in the US are attributed to fibrosis-associated organ damage.

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