Dose-Dependent Effect of Short-Term Repeated Exposure to Amitraz on Some Reproductive Parameters in Male Albino Rats

Authors: Seriki SA*, Adebayo OF and Mbakwe PN

DOI: 10.23880/aabsc-16000125

Volume 2, Issue 1

Abstract

Amitraz is a pesticide used in agriculture and public health to control insects, weeds, animals, and vectors of disease. Although the use of pesticides is of benefit in general, abuse of the pesticides is harmful due to their potential toxicity to humans and animals. Present study examined the effect of the pesticide on the male reproductive parameters of the male albino rats. 20 rats were grouped into four. Group 1 was control, Group 2 was given low dose Amitraz, Group 3 was median dose, and Group 4 was high dose. The administration was for a period of 21 days. Results showed that Amitraz has dose dependent toxicity effect on the reproductive parameter of the rat. Amitraz is toxic to the reproductive parameters of the albino rat, and could lower sperm concentration, sperm motility, and sperm morphology. By implication, Amitraz is toxic to the reproductive system and could cause infertility in male.

Keywords: Infertility; Sperm Concentration; Toxicity; Pesticide; Repeated Exposure

View PDF