Evaluation of Vascular Changes by Optical Coherence Tomography Angiography in Patients with Asymmetric Glaucoma

Authors: Vallejo E*, Gómez HF, Martínez LC and Arias S

Volume 4, Issue 2

Abstract

Objective: To determine differences in vascular density of macular, disc and peripapillary areas measured by optical coherence tomography angiography (OCT-A) in patients with asymmetric glaucoma. Methods: Retrospective, observational study. Charts of patients diagnosed with asymmetric glaucoma, with reliable 24-2 Humphrey perimetry, optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) between February and September 2017 were evaluated. The worse eye of each patient was considered the study eye while the best one was considered the control. There was a statistically significant difference between the eyes regarding the structural and functional metrics. Results: A total of 30 clinical records of patients who met the inclusion criteria were included. The median age was 63 years (33-81), 18 women (60%) and 12 men (40%). The predominant ophthalmological diagnosis was primary openangle glaucoma (70%), followed by secondary glaucoma (16%) and chronic angle closed glaucoma (14%). The vascular density was significantly lower in all regions (macular, disc and peripapillary) by optical coherence tomography angiography, in all the regions evaluated in the study eyes compared to the controls (Wilcoxon Test p <0,05). Conclusions: Optic coherence tomography angiography identified lower vascular density in the studied eyes with asymmetrical glaucoma; this reduction was progressive as the severity of glaucoma increased.

Keywords: Optic Coherence Tomography Angiography; Glaucoma; Visual Field

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