Competitive Binding of AD Agents to Scalp from Shampoo - A Novel Method for Evaluation

Authors: Aruna V*, Soundharya R, Amruthavalli GV and Gayathri R

Volume 3, Issue 1

Abstract

The present study describes a new method of evaluation of the competitive binding of the actives in AD shampoo. We have used Banana silk cloth and Velvet cloth to evaluate the extend of adsorption of actives from shampoo when shampoo contact with the cloth. Further spectrophotometric conformation of the actives in the residue in banana silk cloth and velvet cloth were also evaluated. Similarly, the microbial avoidance test was performed to test the therapeutic value of the actives adsorbed in the test material. Study findings clearly showed that our method is cost effective, rapid, less time consuming and reproducible for evaluating the anti-dandruff performance of shampoo. The above method also gives a comparable simulation model for scalp. Details are presented in the article.

Keywords: Dandruff; Shampoo; Climbazole; Zinc pyrithione

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