International Journal of Biochemistry & Physiology (IJBP)

ISSN: 2577-4360

Editorial

Inhibitory Molecular Interactions of Pyrimethamine Derivatives Versus Malaria Disease

Authors: Mishra S*

DOI: 10.23880/ijbp-16000163

Abstract

Malaria is an acute disease caused by mosquito, having been a major global health problem of humans and a leading cause of mortality across various tropical and subtropical countries. Over the two decades rehabilitated efforts made to control malaria have reduced the occurrence of malaria by over half, but the still its persistence, harshness and appearance of resistance to existing drugs, there is a requirement to develop certain novel drugs to fight against this life threatening disease. Malaria is caused by infection with protozoan parasite, namely, Plasmodium transmitted by female Anopheles species of mosquitoes. Presently, six Plasmodium species viz. Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale curtisi, Plasmodium ovale wallikeri, Plasmodium malariae, Plasmodium knowlesi. Plasmodium falciparum is generally considered the most important in terms of mortality.

Keywords: Malaria Disease; Mosquito

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