Authors: Michael F*
Many cancer drugs are mostly designed with the intent of targeting proteins deregulated in cancer. Seldom are drugs designed to target lipid composition changes in cancer. Whilst targeting proteins seems rational (because they provide diverse function to the cell and are the 'workhorse' of the cell), considering lipids in regards to cancer treatment could provide treatment alternatives. The purpose of this review is to shed light on the role of lipids in cancer and to provide insight into how lipids could be targeted to treat cancer.
Keywords: Many cancer drugs are mostly designed with the intent of targeting proteins deregulated in cancer. Seldom are drugs designed to target lipid composition changes in cancer. Whilst targeting proteins seems rational (because they provide diverse function to the cell and are the 'workhorse' of the cell), considering lipids in regards to cancer treatment could provide treatment alternatives. The purpose of this review is to shed light on the role of lipids in cancer and to provide insight into how lipids could be targeted to treat cancer.
