Rediscovery of Apitherapy Mechanisms: A Novel Challenge in Cardiovascular Autonomic Neuropharmacology

Authors: Miran KR*

DOI: 10.23880/nnoaj-16000134

Volume 4, Issue 1

Abstract

Apitherapy is the scientific term which refers to the medical use of honey, bee venom, propolis, royal jelly, bee pollen, beeswax and apilarnil. Bee venom therapy for arthritis, autoimmune and neurodegenerative diseases is the most wellknown. Numerous studies supported honey for healing of wounds and burns, and even as an anticancer agent. Moreover, several studies evaluating the cardiovascular effects of honey bee products revealed very promising results, paradoxically, apitherapy is still not in focus with a cardiovascular neuropharmacological viewpoint. In an effort to provide extensive information about the cardiovascular bioactivity of natural honey, as the major honey bee product, both in terms of familiarity and profit, this review overviews, for the first time; (1) cardioactive and vascoactive effects of natural honey, (2) mechanisms underlying cardioactive and vasoactive potentials of natural honey, and (3) how improving our knowledge of the mechanisms mediating protective and ameliorative outcomes of natural honey may lead to novel therapeutic strategies for the treatment of cardiovascular diseases? Future challenge remaining will be to permit full exploitation of apitherapy potency to expand novel horizons in the cardiovascular autonomic neuropharmacology.

Keywords: Cardiovascular Autonomic Neuropharmacology; Antihypertensive Effect; Antiarrhythmic Effect; Ameliorative Effect to Cardiovascular Risk Factors; Biotherapy; Apitherapy

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