ISSN: 2474-9230
Authors: Dwajani S and Rupakala BM*
Introduction: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in reproductive women and leading causes of female sub fertility. Symptoms include amenorrhea, infertility, anovulation with irregular menstruation, and excessive release of androgenic hormones. When compared to normal women, PCOS patients have higher serum Anti-Mullerian hormone (AMH) levels, along with increased serum androgens and higher number of small-antral follicles. Objective: This study seeks to explore the effectiveness of previous literature on usefulness of testing serum levels of, LH, FSH in comparison with AMH for a period of 3 months of treatment. Methods: Prospective and cross sectional study, conducted from march 2017 to Oct 2018. 100 women reporting to OBG clinic with inclusion criteria were , Age group: ≥ 18 to ≤ 40 years, Patients complaining of irregular menstruation,amenorrhea and infertility, while exclusion criteria were women with any other co morbid conditions, receiving any medications, Pregnant, lactating and post-menopausal women. We divided them into two groups of 50 each. Group 1 was analyzed for LH, FSH, and scanning (as routine) and group 2 were analyzed for LH, FSH, AMH and scanning (as routine). The blood was centrifuged, separated and analyzed at Central laboratory. To compare between LH, FSH with AMH, we use USG scan as standard diagnostic tool to prove the efficacy of AMH. Conclusion: Our results showed that serum AMH has significant increase in PCOS compared to serum LH and FSH levels. Our findings conclude that AMH is good clinical parameters that can be used for diagnostic testing of PCOS.
Keywords: PCOS; Follicle Stimulating Hormone; Luteinizing Hormone; Anti-Mullerian Hormone
