Thymoma B2 without Myasthenia Gravis or Any Autoimmune Disorder-A Case Report

Authors: Ajith DJ*, Mashhadi M, Wesley H and Peter S

Volume 4, Issue 2

Abstract

The association of Thymoma with Myasthenia Gravis (MG) is well known. Thymoma without MG or any auto immune disease is however, very rare. Since these tumors arise from thymocytes which are immature T lymphocytes of different maturation which has antigen expression profile. Thymoma B1 and B2 are more commonly associated with MG and immunehistochemical analysis play a vital role in differentiating these thymoma types. Our case showed positivity for PANCK, CD57 and negativity for SMA, Desmin, Vimentin, HMB45, EMA, CK7, S100 and CD5. We present an interesting case of Thymoma B2 without pre-operative MG and no evidence of MG for five years of follow up.

Keywords: Immunohistochemistry; Thymocytes

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