Cutaneous Gamma Delta T cell Lymphoma Leading to Hemophagocytic Lymphohistiocytosis that Presented as Posterior Reversible Encephalopathy Syndrome

Authors: Kavya K*, Matthew G, Yu Y, Jimmy R and Zanetta L

DOI: 10.23880/hij-16000142

Volume 3, Issue 2

Abstract

Cutaneous Gamma Delta T cell Lymphoma (CGDTCL) is an extremely rare and aggressive disease arising from immature T cells with gamma delta T cell receptors. CGDTCL can result in a life-threatening syndrome called Hemophagocytic Lymphohistiocytosis (HLH). HLH is a syndrome of fevers, cytopenia and multiorgan failure resulting from excessive immune activation. Early diagnosis of HLH is vital as a delay in diagnosis/treatment may result in grave outcomes. Our patient presented with Posterior Reversible Encephalopathy Syndrome (a syndrome characterized by headache, confusion, seizures and visual disturbance) prior to the diagnosis of HLH.

Keywords: HLH; PRES; Ferritin

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