Cell & Cellular Life Sciences Journal (CCLSJ)

ISSN: 2578-4811

Review Article

The Effect of HIV/HPV on the Structure of the Placental Villi

Authors: Olivar C Castejon S* and Angela J Lopez G

DOI: 10.23880/cclsj-16000145

Abstract

A placenta obtained of patient with co-infection HPV/HIV antiretroviral therapy and serology negative for another illness was analysed with the purpose of demonstrate the effect of this infection on the structure of the placental villi. The features of patient, the diagnostic, methods used, exam of material with H&E stain and sampling was done according morphological criterion of the literature as written in a previous article. Villi with interrumped syncytium are seen communicating the stromal region with the intervillous space. A group of them are associated by fibrinoid deposition, cells of the cellular island lack of cytoplasm, severe changes are observed in stem villi, many placental ramifications are immature, zones of calcification are observed and numerous remainders of villi are noted. The presence of this viral combination has provoked a strong attack to the structure of the villi which put in danger the normal interchange of gases and nutrients in the maternal-fetal intervillous space.

Keywords: Co-infection HPV/HIV; Histopathological changes; Placental villi

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