Virology & Immunology Journal (VIJ)

ISSN: 2577-4379

Review Article

Beta-Lactamases and ESBL

Authors: Abdelmoktader A* and El Far AT

Abstract

Microbial resistance through extended-spectrum β-lactamase (ESBL) was first reported in the early 1980s in Europe and subsequently in the United States soon after the introduction of third-generation cephalosporins in clinical practice. β -Lactamases are enzymes that inactivate β -lactam antibiotics by opening the β-lactam ring of penicillins and cephalosporin and abolish their antimicrobial activity. Beta-lactamases have been described for many species of grampositive and gram-negative bacteria. Some β-lactamases are plasmid mediated while others are chromosomally mediated.

Keywords: Esbl-Î’ -Lactamases-Tem; Shv; Ctx-M; Toho; Oxa; Per; Veb-1; Bes-1 Beta Lactamases

View PDF

F1 europub scilit.net

Chat with us on WhatsApp

Welcome to Medwin Publishers. How can we help you today?