Effect of GABA on Hematological, Biochemical, Antioxidant and Immunological Parameters in Laying Hens

Authors: Elkomy A, Zahra A, Belih S, Shaheen Y, Abugomaa A, Elbadawy M* and Aboubakr M*

DOI: 10.23880/apct-16000170

Volume 4, Issue 4

Abstract

The present work investigated the effect of GABA on hematological, biochemical, antioxidant and immunological parameters in laying hens. Sixty Lohmann Brown laying hens (32 weeks old) were randomly allotted to 3 groups (each 20) and given the medications daily for 4 weeks in drinking water. The groups were; control (without drug), GABA (40 mg/kg b.wt) and GABA (80 mg/kg b.wt). Layers were estimated to complete blood picture, Hb, differential leucocytic count, antioxidant parameters, cholesterol, HDL, LDL, cortisol, haptoglobin, IGG, and epinephrine. There was a significant increase in RBCs, Hb, HDL, SOD, GSH, and IGG while a decrease in MDA, cholesterol, and LDL following GABA supplementation. In conclusion, GABA had a beneficial effect on blood picture, differential leucocytic count, antioxidant parameters, IGG, and haptoglobin.

Keywords: Antioxidant; Blood picture; Chickens; GABA; Layers; Immunity

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