ISSN: 2689-7822
Authors: Lotfali E*, Deravi N, Fathi M, Vakili K, Ghasemi R and Fattahi A
Candida species are fungal pathogens that may cause systematic or superficial infections in the human host and threaten human health. These pathogens are also known by their ability to construct a biofilm structure on biotic or abiotic surfaces. According to their high antifungal resistance, Candida biofilms are hardly eradicated. Actually, this biofilm forming ability, protects them from antifungal drugs as same as host immune system and helps them survive under unfavorable environmental condition. Recent researches have enlightened the biofilm formation mechanism and specified many biofilm markers; in order to prevent their development. Although these studies have been helpful in so many ways, but molecular mechanisms, controlling biofilm formation and pathogeniciy still remains unclear. This review focuses on information’s which are already known of Candida biofilm development, antifungal resistance and genomics
Keywords: Candida; Biofilms; Antifungal Resistance
