Pediatrics & Neonatal Biology Open Access (PNBOA)

ISSN: 2640-2726

Case Report

Prenatal Diagnosis of Fetal Goiter: Case Report and Review of Literature

Authors: Croce P1*, Nava A2, Perotti D, Zanchi SM, Arena B, Croce E

DOI: 10.23880/pnboa-16000143

Abstract

Pregnancy hyperthyroidism due to Plummerâs disease is an uncommon event. Therapy is based on propylthiouracil (PTU), starting from the first trimester of pregnancy. Among the complications of the antithyroid drugs (ATDs) there is the risk of hypothyroidism and fetal goiter, in addition to well-known possible teratogen effects. Maternal hormonal monitoring with a personalized pharmacological treatment and fetal ultrasound control, starting from the 18th week of pregnancy, are mandatory for the mother and fetus health and therefore for a successful pregnancy. In this paper well describe the case of a woman with toxic adenoma, in which the ultrasounds diagnosis of fetal goiter at the 29th gestational-week of pregnancy and the consequent suspension of the ongoing therapy with PTU, succeeded in the end of the pregnancy with the birth of a healthy fetus.

Keywords: Fetal goiter; Maternal hyperthyroidism; Anti-thyroid drugs; Propylthiouracil

View PDF

Google_Scholar_logo Academic Research index asi ISI_logo logo_wcmasthead_en scilitLogo_white F1 search-result-logo-horizontal-TEST cas_color europub infobase logo_world_of_journals_no_margin