Prenatal Diagnosis of Fetal Goiter: Case Report and Review of Literature

Authors: Croce P , Nava A , Perotti D , Zanchi SM , Arena B and Croce E

DOI: 10.23880/pnboa-16000143

Volume 4, Issue 2

Abstract

Pregnancy hyperthyroidism due to Plummer’s disease is an uncommon event. Therapy is based on propylthiouracil (PTU), starting from the first trimester of pregnancy. Among the complications of the antithyroid drugs (ATDs) there is the risk of hypothyroidism and fetal goiter, in addition to well-known possible teratogen effects. Maternal hormonal monitoring with a personalized pharmacological treatment and fetal ultrasound control, starting from the 18th week of pregnancy, are mandatory for the mother and fetus’ health and therefore for a successful pregnancy. In this paper we’ll describe the case of a woman with toxic adenoma, in which the ultrasounds diagnosis of fetal goiter at the 29th gestational-week of pregnancy and the consequent suspension of the ongoing therapy with PTU, succeeded in the end of the pregnancy with the birth of a healthy fetus.

Keywords: Fetal goiter; Maternal hyperthyroidism; Anti-thyroid drugs; Propylthiouracil

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