Mini Review: Pharmacokinetics Changes During Childhood, Old Age and Pregnancy

Authors: Rami­rez Gomez XS*, Jimenez Garcia SN, Beltran Campos V, Garci­a Campos ML and Ortega Jimenez MC

DOI: 10.23880/oajpr-16000189

Volume 3, Issue 4

Abstract

In the different stages of life, various anatomical and physiological changes occur and can influence the responses to drugs, due to pharmacokinetic processes also change with age. In this context, it is important to analyze how the anatomical and physiological changes influence the absorption, distribution, metabolism, and elimination of drugs during childhood, old age and pregnancy with to obtain the best pharmacological response without effects adverse when drugs are prescribed in these populations. Therefore, this review shows general aspects of each pharmacokinetic parameter, as well as special considerations on the absorption, distribution, metabolism and elimination process of drugs in the child, in the elderly and in the pregnant woman to obtain therapeutic success and prevent both therapeutic failure and the toxicity.

Keywords: Pharmacokinetics parameters; Child; Elderly people; Pregnancy

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