Small Cell Carcinoma of the Cervix: About Two Cases and Literature Review

Authors: Bouziane A*, Alami A, Ait Erraisse M,Youssoufi Moulay A, Astaoui F, Farhan Fatima Z, Alami Z, Bouhafa T and Hassouni K

DOI: 10.23880/ijnmrs-16000119

Volume 2, Issue 2

Abstract

Neuroendocrine carcinomas with small gynecological cells are unusual, given their rarity and the absence of randomized trials, the diagnostic and therapeutic management of these tumors is difficult and is essentially modeled on that of pulmonary neuroendocrine tumors. Methods: We report two new cases of small cell cervical neuroendocrine carcinoma and through the literature data we review the different aspects of this rare entity, both patients had a tumor stage IB2 and IIIC, the first The patient received RCC, followed by surgery, then postoperative brachytherapy, supplemented with adjuvant chemotherapy, and the second received RCC followed by brachytherapy. Results: Both patients died within 6 to 18 months after the end of chemoradiotherapy following metastatic recurrence. Conclusion: Despite multimodal treatment, the prognosis of neuroendocrine carcinomas remains unfavorable.

Keywords: Small Cell Neuroendocrine Carcinoma; Cervix; Radiation Therapy; Chemotherapy

View PDF