ISSN: 2578-4676
Authors: Qazaryan KSY*, Akash NSY, Zebari HS and Salih QM
Purpose: The goal of our research study is to prove that Vit D supplementation on children with frequent UTI has clinical effective role in the treatment and pathogenesis of the disease and that Vit D and UTI are strongly clinically linked. Methods: This is case-control research study, 130 children aged 0-18 y with recurrent UTI were involved (case group) and compared with 130 children (control group) considering serum Vit D level measurement and following up participants for 9 months. ELISA (enzyme-linked immunosorbent assay) was used to measure serum Vit D level. The results data were analyzed to compare between both case and control groups. Results: In our study and among 130 children aged 0-18 y with recurrent UTI (case group), 35 (27%) were boys and 95 (73%) were girls, and in healthy participants (control group) 42 (32%) were boys and 88 (68%) were girls consequently. The mean serum Vit D level in the case group before starting this research study was (8ng/ml) in 62% and the incidence of frequent UTI was more than 10 times/month in 79%; after administration of 1000-5000 IU of Vit D, a remarkable raise of Vit D (22ngml) in 59% with decline incidence and frequency (less than 3 times/month) of UTI has been reported in 74%. Conclusion: In our case-control study, based on our results and data, we reported that Vit D supplementation in children with frequent UTI has very good clinical effective role in the treatment and elimination of the incidence of UTI in such cases. Adequate relatively high effective dose of Vit D (1000 IU-5000 IU) must be administered in children with UTI according to age and severity, this supplementation has very significant key role to decline the incidence, frequency as well as the common clinical symptoms and signs of UTI in children aged 0-18 y.
Keywords: Children aged 0-18y; Vit D adequate dose; Recurrent UTI
