Biogenically Fabricated TMO-NPs and their Anti-Bacterial and Fungal Assay (Well Diffusion Method) in Saline Solution

Authors: Madiha Batool

Volume 5, Issue 1

Abstract

Nanotechnology has attained a great deal of attention in the scientific circle. MO-NPs like copper oxide and zinc oxide, and ironoxide had been used in industry for different purposes, like paints, cosmetics and plastics. A recurrent feature that TMO-NPs exhibit is antimicrobial and fungal behavior against gram positive and negative bacteria. In this research work, we experimented the antimicrobial and antifungal activity of transition TMO-NPs nanoparticles against Gram-positive and Gram-negative bacteria. Nanosized Transition metaloxides (TMO) particles like ironoxide, copperoxide, zincoxide were biogenically synthesized by using Aloe Barbadensis leaves extract and characterized by XRD, FTIR, and TEM techniques. XRD confined the single-phase fabrication of metal oxides nanomaterials. The size of metal oxides ranges between 9-20nm. We applied these synthesized nanomaterials to assess their antibacterial and antifungal activity against E.coli, B.Subtilis, B.Licheniformis, K.Pneumonia, Aspergillus Nigar, Candida Albicanes bacteria sand fungui.: Among the MO-NPs, ZnO (zincoxide) exhibited highest antimicrobial activity against GP and GN bacterias described above in this research, while hamatite nanoparticles exhibited the lowest ZOI. Copperoxide nanoparticles demonstrated moderated results of anti-bacterial and antifungal activity.

Keywords: Nanomaterial; XRD; Antibacterial Activity; Metal Oxides; Antifungal Activity

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