Treatment of Cutaneous Leishmaniasis with Photodynamic Therapy: The First Case Report from Khyber Pakhthunkhwa (KPK), Swat Pakistan

Authors: Khan A, Khan K*, Biradar G, Ali A and Khan M

DOI: 10.23880/cdoaj-16000203

Volume 5, Issue 1

Abstract

Background: Cutaneous Leishmaniasis (CL), the most common subtype of Leishmaniasis, is a vector borne disease transmitted by sand fly. Case Presentation: Herein, we report a case of CL and, for the first time, its treatment with photodynamic therapy (PDT) in KPK, Pakistan. Specifically, a 55-year-old female patient presented with a single chronic disfiguring ulcerated lesion on the chin. The patient had received pentavalent antimoniate for the last 2 years, with no satisfactory outcome. We treated the patient with methylaminolevulinate based PDT and observed complete response after three session of the PDT treatment, each with a light energy dose of 75 J/cm2. Conclusion: The patient has remained disease-free for over 2 years. This study demonstrates the promising role of PDT in the treatment of CL.

Keywords: Cutaneous leishmaniasis; Photodynamic therapy; Pentavalent antimoniate; Photosensitizer; Methylaminolevulinate

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