Gastroenterology & Hepatology International Journal (GHIJ)

ISSN: 2574-8009

Research Article

Clinico- Pharmacologic Score Predicting Outcomes in Hospital Admitted Patients: Study from a Tertiary Centre

Authors: Sharma R , Nagaich N and Niranjana N

DOI: 10.23880/ghij-16000169

Abstract

Objectives: To determine the association between clinico- pharmacologic score (CPS) and clinical outcomes in patients admitted in critical care (≥45 y), focusing on outcome prognostication. Methods: A retrospective study of patient’s of ages ≥ 45 years was performed using a Hospital database. The study period was from 1st August 2017 to 31st August 2018. Data gathered included patient demographics, injury severity score (ISS), Glasgow coma scale (GCS), hospital and intensive care unit lengths of stay (HLOS and ILOS, respectively), home preinjury medications (prescription and over the counter), morbidity, comorbid conditions and in-hospital mortality. Then according to CPS ranges, patients were divided into four groups and then to two groups (for statistical purposes). Results: The variables for the 205 patients included in the study, were analyzed. The mean patient age was 72.4 ± 13.1 years. Males represented 52 % of the study sample. Mean GCS was 13.2 ± 1.8, mean ISS was 9.4 ± 6.9 and mean number of medications per patient was 3.6±1.5 (range 0-16). The independent predictors of mortality included age (AOR 1.21, 95 % CI 0.98-1.038, p

Keywords: Polypharmacy; Injury Severity; Clinico Pharmacologic Score

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