ISSN: 2577-4328
Authors: Tabassum Zafar
Novel coronavirus-19 (nCoV-19) is a positive-sense single-stranded RNA virus that belongs to the virus family responsible to spread severe acute respiratory syndrome (SARS)[1]. This virus consists of envelope protein (E-protein), nucleocapsid protein (N-protein), spike protein (S-protein), membrane protein (M-protein) and a number of accessory open reading frame proteins (ORF proteins). Angiotensin converting enzyme-2 (ACE2) is the prime endogenous membrane protein that plays an important role in nCoV-19 infection. The virus binds to its host via its trimeric spike glycoprotein structure, which is ten times stronger attachment than SARS [2]. Now, we all are under the threat to face the emerging pandemic of nCoV-19 outbreak, which declared as Public Health Emergency of International Concern by World Health Organization (WHO).
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