ISSN: 2573-1734
Authors: Chandra S*, Yadav S, Kori S, Anjana and Shinde LP
Mosquito repellents such as vaporizers, mats, coils and creams are being used in the household to reduce the risk of dengue, chickungunya and other infectious diseases. Nowadays liquid mosquito repellent is very common in the society due to easy availability, low cost and easy to use it remains available in most of the houses but its misuse in suicide/homicides cases cannot be ruled out. Toxicity of repellents results mainly in central nervous system (CNS) symptoms like headache, dizziness, drowsiness, status epilepticus and respiratory failure. A case of unknown poisoning was reported in 62 year old deceased and an empty repellants bottle was found at scene of crime. In this study various solvent systems have been tried to detect transfluthrin in biological material by using thin layer chromatography (TLC). It was observed that Benzene: Hexane (1:1) solvent system found very close Rf value with reference to standard transfluthrin in comparison to other solvent systems. The confirmation compound was carried out by FTIR and Gas Chromatography Mass Spectrometry (GC-MS) methods. The developed solvent system was found the quick, easy and cost effective for detection of transfluthrin in biological material. It has also been found that the concentration of the transfluthrin prevalent in the in tissues of liver and kidney, lowest levels was found in the brain.
Keywords: Transfluthrin; Viscera; Case study; TLC; FTIR; GC-MS
