Unusual Case of Pyoderma Gangrenosum and Bilateral Ear Changes Secondary to the Use of Cocaine with Levamisole in a Patient with Systemic Lupus Erythematodes

Authors: Manov A*, Dhanabalsamy N and Hapuarachchi M

DOI: 10.23880/abca-16000116

Volume 3, Issue 2

Abstract

Levamisole has been considered an adulterant in cocaine and increasingly reported as the cause for many of the complications noted in cocaine users [1-3]. The main reason for intentionally adding this compound to street cocaine has been due to its effect to potentiate the sympathomimetic effects of cocaine. The exact mechanism by which this agent causes complications is unclear. We present a unique case of a cocaine user who presented with acute non-healing skin lesions, ear changes, inflammatory monoarthritis and other systemic signs with subsequent workup leading to the diagnosis.

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