ISSN: 2574-7770
Authors: Nole T* and Wilfried Lionel TD
Background: Hyperglycemia-induced oxidative and inflammatory harm are the major causes of chronic and fatal complications of diabetes. In many developing countries the products of socio-cultural medicine are more used by low income populations to fight against diseases particularly diabetes. The economic crises, the slump of agricultural product’s prizes and the significant increase of the population, are at the origin of the strong dependence on African traditional medicine. Objective: The objectives were to identify factors that influenced the better uses of potential bioactive plants published by Cameroonians, particularly used for diabetes management in order to select those that can improve insulin sensitivity and can be principally used to avoid diabetic complications. Methods: To achieve this objective, the review was carried out in online databases including Google, Google Scholar and Pubmed, between 2018 and 2019. For the ethnopharmacological standardization of recipes, we proposed in this work the doses calculated by deduction from the doses used to treat in vivo alloxan or streptozotocin induced diabetic rats. The presence of one or several antihyperglycemic compounds in recorded plants and the hypoglycemic effects of their extract reinforced the herbal use of these species. Results: All the admitted plants exhibited antidiabetic properties. Twenty-eight point fifty-seven percent (28, 57%) of them were confirmed antihyperglycemic and improved insulin sensitivity. Permanent stress is the important factor influencing the better management of diabetes by these plants. 1.5. Conclusion: The results of this study can be the scientific basis for antidiabetic drugs discovery that can prevent insulin resistant and consequently complications of diabetes type 2.
Keywords: Anti-diabetic Plants, Potential Antihyperglycemic plants, Adequate conditions for their good uses, Bioactive Antidiabetic Compounds, Insulin Resistance, Cameroon
