ISSN: 2642-6250
Authors: Eftimie LG, Costache DO, Uscatu CD*, Glogojeanu RR and Costache RS
Non-melanoma skin cancer (NMSC) comprises squamous cell carcinoma (SCC), basal cell carcinoma (BCC), and several rare skin tumors (i.e., Extramammary Paget’s disease), being the most common malignancy affecting people worldwide. It represents the majority of skin cancers and a significant percentage of all malignancies. Despite increasing public awareness and scientific interest, the incidence of NMSC is constantly increasing. Even though most NMSC`s are associated with less aggressive behavior, they can still be invasive locally and cause extensive damage to neighboring structures, inducing significant morbidity. Also, different types and subtypes of NMSC tend to have frequent recurrences and may have significant metastatic potential. As a direct consequence, NMSC has become an important issue for healthcare systems with a significant socio-economic impact.
Keywords: Extramammary Paget’s Disease; World Health Organization; Keratinocyte Stem Cells; EMA
