ISSN: 2474-9230
Authors: Kulvinder Kochar Kaur*, Allahbadia GN and Singh M
The chances of live birth following in vitro fertilization (IVF) have plateaued despite lot of advances. A lot of extra therapies are available that suggest a lot of effectiveness in enhancing the success of IVF. The idea of this review is to detail whether any benefit is there regarding the add ones utilized with the idea of increasing endometrium receptivity. We included systematic reviews of randomized controlled trials (RCT’s) including separate trials. Basically 5 add ones were scrutinized namely Immune therapies comprising of corticosteroids, Intravenous Immunoglobulin (IVIG) Granulocyte-Colony Stimulating Factor (G-CSF), as well as intralipid, Endometrial Scratching; Endometrial Receptivity Array (ERA); Uterine Artery Vasodilation including Platelet rich plasma (PRP) as well as Intrauterine Human Chorionic Gonadotropins (HCG). The results point that no strong proof is there that such add on are efficacious as well as safe. Many of these are expensive and it is better to use that money for any treatment that has been proven by evidence. Need for large RCT’s as well as proper safety examination are a must before they get used during routine clinical practice.
Keywords: HIV; Syphils; ASTEL Kit; Dual testing
