A Rare Case of Apert Syndrome due to Mutation of FGFR2 Gene (Fibroblast Growth Factor Receptor 2) – A Disorder of Advanced Paternal Age- A Case Report

Authors: Mukhopadhyay S*

DOI: 10.23880/oajg-16000192

Volume 5, Issue 1

Abstract

The effects of advanced maternal age on offsprings have been well studied and the best documented example is Down syndrome. A small group of congenital disorders, called paternal age effect (PAE) disorders include Apert syndrome, Crouzon syndrome, Achondroplasia and Thanatophoric dysplasia are associated with increased paternal age, relative to the general population. One such case of Apert Syndrome has been discussed in this article.

Keywords: Paternal Age Effect; Fibroblast Growth Factor Receptor 2 Mutation; Selfish Selection; Mutant Seminiferous Stem Cells

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