Medicinal & Analytical Chemistry International Journal (MACIJ)

ISSN: 2639-2534

Research Article

Isolation of Three New Substituted Disaccharides from Leaves and Stems of Phlox Drummondii

Authors: Huma Aslam Bhatti*, Aneela Naz, Rubina, Samina naz and Shaheen Faizi

DOI: 10.23880/macij-16000161

Abstract

We currently work with fresh, undried and uncrushed flowers, leave and stems which were used to avoid the formation of artifacts through aerial oxidation and enzymatic degradation. These studies have led to the isolation of three new constituents. 2-O-(β-3′-O-acetyl,4′-O-isovaleroyl-rhamnopyranosyl)-1-O-hexyl,3-O-acetyl-β-xylopyranose (Compound 1), 2-O-(β-2′,3′- Di-O-acetyl,4′-O-isovaleroyl-rhamnopyranosyl)-1-O-hexyl,3,4-di-O-acetyl-β-xylopyranose (Compound 2) and 2-O-(β-3′-Oacetyl,4′-O-isovaleroyl-rhamnopyranosyl)-1-O-hexyl,3,4-di-O-acetyl-β-xylopyranos, along with one known 4-hydroxy benzoic acid have been isolated from the leaves and stems of Phlox drummondii. Their structures have been established through chemical and spectral studies including two dimensional NMR (COSY 450, NOESY, HMQC and HMBC) experiments.

Keywords: Phlox drummondii; Polemoniaceae; Xylopyranose; Rhamanose

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