Is It Time to Switch the Focus of Murine Studies to Treatment Rather than Prevention in Abdominal Aortic Aneurysms?

Authors: Morgan Salmon*

DOI: 10.23880/oajc-16000151

Volume 4, Issue 1

Abstract

While there is a growing body of evidence to suggest possible mechanisms for Abdominal Aortic Aneurysm (AAAs) formation, few murine studies have identified successful translational targets for AAA therapy in patient settings. This commentary seeks to address the need for murine studies to focus on treatment of established AAAs in multiple models to have the best possible outcome for future patient intervention. 

Keywords: Abdominal Aortic Aneurysms; Murine Studies; Transforming Growth Factor Beta

View PDF