ISSN: 2640-2653
Authors: Sourav Kumar Kundu, Md Ferdous Seraj, Md Mohasin and Tania Rahman*
Dengue, a mosquito borne viral infection is a leading cause of acute flu-like illness occasionally develops into a potentially lethal complication. DENV, the virus responsible for causing dengue has become prevalent in recent years with a million of infection as well as a couple of thousand deaths in the tropical and subtropical climates worldwide. The four strains of dengue virus identified so far among which DENV-II and DENV-III are more prevalent in Bangladesh have some common distinctive symptoms. As dengue symptoms are most of the time not intense and sometimes asymptomatic, differentiating dengue patients from patients with acute febrile illness is a great challenge and it is tough to identify at the preliminary stage. The dramatic rise of global incidence of dengue infection has generated an urgent yet an unmet need for an accurate and validated rapid diagnostic test for DENV infection. In this review, we survey and analysis our current knowledge and relative understanding of the epidemiology of dengue virus, its classification, clinical manifestation of dengue fever, its pathogenesis and clinical diagnosis of dengue.
Keywords: Dengue virus; DENV infection; Flu; Flavivirus
