COVID-19 Male Patients with Gastrointestinal Symptoms are at Higher Risk of Poor Clinical Outcomes but Not Mortality in Low Prevalence Areas

Authors: Dalessio S, King S, Pinchuk I, Howrylak JA, Clarke K and Al-Sadi R*

Volume 5, Issue 2

Abstract

COVID-19 has been reported to cause gastrointestinal (GI) manifestations. However, there is limited data regarding the association between GI symptoms and clinical outcomes including mortality in low population density. Using TriNetX, a real-time analysis was performed for patients diagnosed with COVID-19 at Penn State Milton S. Hershey Medical Center. Our study, including a cohort of male and female patients (220), showed that the Covid-19 male patients with GI symptoms have higher risk for respiratory failure and hospitalization, but not mortality, compared to male patients without GI symptoms or female patients (with or without GI symptoms). Our study provides unique perspective of the impact of Covid-19-related mortality in low-density areas independent of GI symptoms.

Keywords: COVID-19; Gastrointestinal Symptoms; Respiratory Failure; Mortality

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